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5 grants for doctoral thesis in Dept. of Medical Microbiology and Hygiene, University Hospital Heidelberg.

Within a new postgraduate program “Differential activation and integration
of signaling modules within the immune system“, funded by the postgraduate
education program of Baden-Württemberg,

5 grants for doctoral thesis

beginning mid 2008 and with a 3-year duration are available.
The purpose of the program is the analysis of interactions between different
signaling cascades in cells of the innate and the adaptive immune
system. The work will focus on immunology, molecular and cellular
biology. Successful candidates will have an excellent track record and will
be highly motivated with a deep interest in Immunology and signal transduction.

We offer a well-structured and coordinated immunological
education program. We will provide excellent training in many aspects of
molecular and cellular Immunology in a well-equipped environment and
a positive working atmosphere.

Further information on the program and the application procedure can be
found at our website: www.immunesignaling.uni-hd.de

Applications should be sent by e-mail as a single pdf-file to:
immunesignaling@uni-hd.de

Speaker of the program:

Prof. Dr. A. Dalpke,
Dept. of Medical Microbiology and Hygiene, University Hospital Heidelberg,
Im Neuenheimer Feld 324,
69120
Heidelberg,
Germany.

Link: http://www.laborjournal.de/rubric/markt/gesetzt/S_08_04_a23.pdf

Postdoctoral position at The Division of Structural Biology at the Helmholtz Centre for Infection Research in Braunschweig/Germany

The Division of Structural Biology at the Helmholtz Centre for Infection Research in Braunschweig/Germany invites applications for a Postdoctoral position

Planned project: Crystal structure determination of complex multi -modular assembly lines from Myxobacteria

Area of research: Structural biology, natural compound chemistry

Methods: State-of-the-art techniques in recombinant DNA technology (PCR, cloning, protein expression systems, site-directed mutagenesis), protein biochemistry (ÄKTA protein purification, protein analytics, crystallization of proteins), X-ray structural analysis (data collection, structure solution, model building and refinement), structure-function studies on proteins

Prerequisite: PhD in biochemistry, biology or chemistry. Profound experience in protein biochemisty and recombinant DNA technology mandatory. Experience in protein crystallography/structural biology will be advantageous.

Starting date: The position is immediately available but later starting dates are also possible.

Duration: Initially for 3 years with an option for extension

Apply to: Applications marked for Code 15/2008
should be sent by May 31st, 2008 to:


Helmholtz Centre for Infection Research,
Personalabteilung,
Inhoffenstrasse 7,
D-38124
Braunschweig


Applications should contain a CV, list of publications,
copies of certificates and contact information for two
letters of recommendation

Information: For further information please feel free to contact
Prof. Dr. Dirk Heinz (dirk.heinz@helmholtz-hzi.de,
phone: +49(0)531-6181-7000)


Link: http://www.laborjournal.de/rubric/markt/gesetzt/S_08_04_a14.pdf

Post-doc Positions at Goethe University Medical School, Frankfurt, Germany.

Post-doc Positions
at the Institute of Biochemistry II, Goethe University Medical School,
Frankfurt, Germany.

The Institute of Biochemistry II is an interdisciplinary department
focused on signal transduction research. It is equipped with modern
facilities and offers the opportunity to work with leading scientists
in an international and team-oriented environment. Group leaders
include Ivan Dkic, Metello Innocenti, Werner Müller-Esterl, Krishna
Rajalingam, and Ritva Tikkanen. For more information, please visit
our website: http://www.biochem2.de.

We are seeking highly motivated scientists with strong interests in
(I) regulation of actin dynamics, (II) modulation of protein function
through ubiquitylation and (III) signal transduction in embryonic
development. Experience with standard techniques in molecular
biology, protein biochemistry and tissue culture is required. Knowledge
of imaging techniwues will be considered as a plus. Although
English is the official language of the institute, good German
language skills are welcome.

The positions are available initially for a period of 3 years; salary is
according to German BAT IIa (up to 45.000 € p.a. depending on
previous experience).

The legal provisions of the ”Wissenschaftszeitvertragsgesetz“ (law
regulating time limited contracts for scientists) and the ”Hessische
Hochschulgesetz“ (Hessian Law for Higher Education) apply.
Qualified women are partricularly encouraged to apply.

Formal applications should include a letter stating your interests, a
full CV and the names of two referees and should be sent to:
office@biochem2.de. Informal inquiries regarding project details
are invited.

Link:
http://www.biochem2.de.
http://www.laborjournal.de/rubric/markt/gesetzt/S_08_04_a34.pdf

The Max Planck Institute for Immunobiology in Freiburg, Germany.

which is for an initial two-years appointment with the possibility of extension.
The position is available in the Department of Molecular Embryology (Head:
R. Kemler).

The research activities of the department focus on E-cadherin-mediated cell
adhesion and on Wnt/ß-catenin signaling in mouse embryonic development
(http://www.immunbio.mpg.de).

Candidates with experience in these research areas will be at an advantage.
Profound knowledge in protein biochemistry, cell and molecular biology, as
well as in mouse developmental biology is required.

Payment will be a postdoctoral fellowship of the Max-Planck Society.
Women are especially encouraged to apply and handicapped applicants with
equal qualification will be given preferential treatment. A childcare facility
is attached to the Institute. Scientific business at the Institute is carried out
in English.

Applications (by e-mail) should include a curriculum vitae with names of
three references and a list of publications.

Max Planck Institute for Immunobiology, Personnel Department
Stübeweg 51,
79108 Freiburg,
Germany
or weigold@immunbio.mpg.de


Applications will be accepted until June 30, 2008.


For further information please contact
Prof. Dr. Rolf Kemler
Phone: +49-761-5108-471
Fax: +49-761-5108-474
e-mail: kemler@immunbio.mpg.de

Link: http://www.laborjournal.de/rubric/markt/gesetzt/S_08_04_a20.pdf

PhD position at Division of Molecular Genetic Epidemiology, German Cancer Research Center

Applications are invited for a

PhD position

at Division of Molecular Genetic Epidemiology,

German Cancer Research Center

Funding source: Tumorzentrum Heidelberg/Mannheim

Duration: as soon as possible until 31.12.2010

Supervisor: PD Dr Rajiv Kumar

Research work will involve a specific area of cancer genetics leading to

doctoral thesis. The study will include an investigation of genetic variants

involved in the susceptibility of childhood acute lymphoblastic leukemia

identified by genome wide analysis using SNP microarrays. The basis of

project is to identify predisposing genetic factors and role of such genetic

factors in the disease outcome. The project will involve the use of Hap-

Map data to identify haplotypes and tagging single nucleotide polymorphisms

to capture maximum information about the involvement of

haplotypes in risk modulation of the disease. The research work will

involve use of bioinformatics, biostatistics and extensive laboratory work.

The project is being carried out collaboration with Prof. Dr. C. R. Bartram,

Institute of Human Genetics, University of Heidelberg. The funding is

guaranteed for three years.

The required qualifications are diploma in biology or related field; background

in molecular biology and genetics and knowledge of biostatistics

is desirable.

The interested candidates can contact:

PD Dr Rajiv Kumar (Phone: 0049-(0)6221-421806)

Division of Molecular Genetic Epidemiology

German Cancer Research Center

Im Neuenheimer Feld 580

69120 Heidelberg

Germany

Email: r.kumar@dkfz.de

Link: http://www.laborjournal.de/rubric/markt/gesetzt/S_08_04_a46.pdf

Engineer Two-Photon Microscopy in Radboud University Nijmegen, Netherlands.

Department: The Microscopic Imaging Centre (MIC) of the Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen,

The Netherlands is a State-of-the-art facility for imaging of biological specimens utilizing light microscopy (bright-field, confocal, two-photon); scanning and transmission electron microscopy; and digital sample analysis for researchers within and outside the NCMLS.


Job profile: The engineer supports the newly installed two photon in vivo imaging platform (hardware); develops add-ons (f.e. skin windows) to analyze internal mouse tissues/organs (CAD programming); develops automated measurements (macro programming); keeps up to date with relevant scientific and technical literature; trains external and internal users


Requirements: Academic degree in Physics or Biology with background microscopy (or equivalent); relevant computer skills; fluent written and spoken English; enthusiastic and communicative skills


Terms of employment: Temporary 2 years with option to be extended; 36 hrs per week; salary level 10: maximal € 3638 gross per month


Information: Prof. Dr. P. Friedl, head Cell Dynamics Group, +31 24 3610907, p.friedl@ncmls.ru.nl; Dr. J. Fransen, Microscopy facility manager, +31 24 3614284, j.fransen@ncmls.ru.nl


Kontakt: Mw. M. Korsten, HRM counsellor (
155 CBEG, Concerns vacancy: 08484), UMC Radboud, Postbus 9101, 6500 HB Nijmegen, The Netherlands
URL:
http://www.ncmls.nl