A postdoctoral position is currently available at the Clinical Research Group for MS and Neuroimmunology located at the University of Wuerzburg

Call for applications for a postdoctoral position, Call for applications for a postdoctoral position: immuneregulation in the CNS (TV-L equivalent to BATIIa) A postdoctoral position is currently available at the Clinical Research Group for MS and Neuroimmunology located at the University of Wuerzburg, Department of Neurology. We are looking for a creative and motivated postdoc with ambitious career interest and experience in immunology. The work is related to the fundamental mechanisms of immune regulation in the central nervous system, especially the role of novel coinhibitory molecules of the B7-family and the interaction of CNS-antigen-presenting relation with regulatory T cells. Approaches cover experimental animal models using conditional transgenes and ablatable systems as well as various techniques in human cellular and molecular immunology. The work is funded by the Deutsche Forschungsgemeinschaft DFG as part of the Sonderforschungsbereich 581 (Molecular models of nervous system diseases). Please send a letter of application including curriculum vitae, certificates and names and addresses of potential referees to: Heinz Wiendl, MD Professor of Neurology and Head of the Clinical Research Group for Multiple Sclerosis and Neuroimmunology Department of Neurology, University of Wuerzburg Josef-Schneider-Straße 11 97080 Wuerzburg Germany Tel.: + 49-931-201-23755 Fax.: + 49-931-201-23488 E-mail: heinz.wiendl@klinik.uni-wuerzburg.de Secretary for the Clinical Research Group for MS and Neuroimmunology Tel.: +49-9 31-2 01-2 37 56 Recent literature: Magnus T, Schreiner B, Korn T, Jack C, Hong G, Antel J, Ifergan I, Chen L, Bischof F, Bar-Or A, Wiendl H. Microglial expression of the B7-family member B7-H1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS. J Neuroscience 2005; 25(10):2537-2546 Feger U, Tolosa E, Huang Y, Waschbisch A, Biedermann T, Melms A, Wiendl H. HLA-G expression defines a novel regulatory T cell subset present in human peripheral blood and sites of inflammation. Blood. 2007; 110(2):568-77 Meuth SG, Bittner S, Meuth P, Simon OJ, Budde T, Wiendl H. TWIK-related acid sensitive K+ channel 1 (TASK1) and TASK3 critically influence T lymphocyte effector functions. J Biol Chem. 2008; Epub ahead of print Zozulya A, Wiendl H. Mechanisms of disease: the role of regulatory T cells and dendritic cells in Multiple sclerosis. Nature Reviews Clin Practice, In press Lafon M, Megret F, Meuth SG, Romero M, Lafage M, Chen L, Aleopoulou L, Flavell R, Prehaud C, Wiendl H. Detrimental contribution of the immunoinhibitor B7-H1 to rabies virus encephalitis. J Immunol. In press Ortler S, Leder C, Mittelbronn M, Zozulya A, Knolle P, Chen L, Kroner A, Wiendl H. B7-H1 modulates neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of Multiple sclerosis. Eur J Immunol. In press Kontakt: Prof. Dr. Heinz Wiendl (heinz.wiendl@klinik.uni-wuerzburg.de), Neurologische Klinik der Universität Würzburg, Josef-Schneider-Straße 11, 97080 Würzburg , Tel.: 0931-201-23756 , FAX: 0931-201-23488 URL: http://www.klinik.uni-wuerzburg.de/neurologie