A Postdoctoral Scientist and a Technical Assistant at Institute of Virology in Hannover Medical School.

Institute of Virology in the group of Cell Biology of Viral Infections Hannover Medical School (MHH), founded in 1965, is one of the world's leading university medical centres. Our outstanding success in interdisciplinary collaboration both within the MHH and with
extramural scientific institutions is reflected in the fact that the MHH is the German medical university with the largest volume of grant funding. The Institute of Virology hosts 7 research teams funded by the DFG, the EU, Volkswagenstiftung, Wilhelm-Sander-Stiftung and the BMBF and working on important human pathogenic viruses such as the KSHV, HCMV, HSV, HCV, HIV, and adenoviruses.

In the Sodeik team, we study the herpes simplex virus (HSV) infection of epithelial cells and
neurons using digital life-cell imaging and dual-colour fluorescent viral strains, electron microscopy, and biochemical assays reconstituting key aspects of the viral life cycle. Our success in our scientific endeavours’ is built on curiosity, innovation, and diverse approaches to do science. We offer a nice, dynamic team driven by collaborative efforts.

Opening for a Postdoctoral Scientist
Within the ERA NanoSci+ project on Nanocommunication: How viral particles convince cells to let them inside in collaboration with the Vrije Universiteit (Amsterdam), Oxford University and the Israel Technion Institute of Technology (Haifa) we are looking for a highly motivated scientist willing to work in a high-profile international, interactive team.
Your major task will be to analyse the interaction of HSV capsids with the nuclear pore, to identify the host nuclear import and pore factors interacting with HSV, and to understand viral genome release and import into the nucleus on a molecular level. The preferred candidate has a PhD degree and a strong scientific background in biochemistry, cell biology or virology. Hands-on experience studying the nuclear pore complex, RNAi, subcellular fractionation, fluorescence microscopy, and expression of recombinant proteins would be an asset.

Opening for a Technical Assistant, part-time
Within a national program project grant (German Research Council DFG-SPP 1175) on Dynamics of Cellular Membranes and their exploitation by viruses we are looking for a highly motivated assistant running the molecular biology branch of our group. You will be actively involved in our research project studying the function of HSV proteins in virus assembly. Your main responsibilities will be the generation and characterization of new HSV mutants using our bacterial artificial chromosome. You should be familiar with molecular biology techniques, such as cloning,
mutagenesis or quantitative RT-PCR, have a quick grasp on learning new techniques, able to work on your own and known for your accurate but yet efficient working style.

Both positions are available for three years starting in July 2009. Please feel free to call us for
further informal inquiries. Applications including a CV and three letters of recommendation should be sent to Beate Sodeik by June 10th, 2009.
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Prof. Dr. rer. nat. Dipl.-Biol. Beate Sodeik
Institute of Virology, OE 5230, Hannover Medical School
Carl-Neuberg-Str. 1, D-30625 Hannover, Germany
Phone: ++49 - (0) 511 - 532 2846 (office), x 2845 (lab), x 6736 (Institute)
FAX: ++49 - (0) 511 - 532 8736; Email: Sodeik.Beate@MH-Hannover.de
Homepage: http://www.mh-hannover.de/221.html

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