For a European Union funded project on cellular and molecular mechanisms of arrhythmia, we seek a highly motivated student for a PhD project, starting immediately, for up to 4 years. Using advanced methods for gene targeting and transgene construction, candidate mutations inducing muscle arrhythmia will be introduced in the animal model Caenorhabditis elegans. Furthermore, optogenetic methods (Channelrhodopsin and Halorhodopsin) will be used. A university degree (Diploma, Master) in molecular biology, biology, biochemistry, or physiology is required. Solid experience in molecular biology methods is a prerequisite, previous experience with C. elegans, as well as with “recombineering” methods, is highly welcome. For more information, see papers and website (find URL below): EMBO J (2005) 24: 2566; Curr. Biol. (2005) 15: 2279; Nature (2007) 446: 633; Nat. Meth. (2008) 5: 895; EMBO J (2009) doi:10.1038/emboj.2009.204. Send CV, description of research experience and interests, certificates, and references to Alexander Gottschalk, no later than August 16th, 2009.
Kontakt:
Alexander Gottschalk (a.gottschalk@em.uni-frankfurt.de)
Goethe Universität, Institut für Biochemie, Biozentrum N220
Max von Laue Str. 9
D-60438 Frankfurt, Germany
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