A group leader position and a postdoctoral position
are available in the Department of Developmental Immunology.
Current research in the department focuses on the evolution of the adaptive
immune system and the development of the thymic microenvironment (See
our web-site at http://www.immunbio.mpg.de/home/research/immun/
index.html).

Applicants for the group leader position should have completed internationally
recognized post-doctoral research and will be free to choose topics complementary
to the current activities in the department. Innovative research proposals
involving quantitative and/or synthetic approaches to the function of the
immune system or model organisms not yet represented in the department
are particularly welcome.

The group leader position is for an initial 5-year appointment with the
possibility of extension. Technical support and funds for one PhD student
or postdoctoral fellow plus consumables will be provided; applicants are
encouraged to obtain outside funding. Payment and social benefits will be
in accordance with the regulations of the German TVoeD (salary agreement
for public service employees). Group leaders have full access to the excellent
animal (zebrafish/mouse), cell sorting, sequencing and imaging facilities of
the institute.

Applicants for the post-doctoral post should have experience in molecular
biology/immunology and an excellent publication record. The post-doctoral
fellow is expected to work on aspects of the evolution of the immune system
using mice and flies as model systems. Previous experience in fly genetics
is welcome but not essential.

In order to increase the proportion of female staff members, applications
from female scientists are particularly encouraged. The Max-Planck Society
strives to offer more employment for the disabled. Disabled candidates are
encouraged to apply. A childcare facility is attached to the Institute. Parttime
employment is possible.

Applicants should send their CV, list of publications and a brief statement
of research plans and arrange for 3 reference letters to be sent with the
index number 020408 to the Max-Planck Institute of Immunobiology,
Personnel Department, Stuebeweg 51, D-79108 Freiburg, Germany
(weigold@immunbio.mpg.de). Informal inquiries should be directed to Thomas
Boehm (boehm@immunbio.mpg.de). Applications will be accepted until the
vacancy is filled.

We are extending our research group focused on the elucidation of signaling
pathways during renal development and disease, and offer PhD and postdoctoral
positions to qualified scientists with experience in molecular and/
or developmental biology. Highly motivated PhD students with a master/ diploma
degree in biology, biochemistry or related life sciences are welcome
to apply. The positions are immediately available at the Center for Clinical
Research / Molecular Nephrology (Director: Prof. Dr. Walz). As part of a
multidisciplinary team you will work closely with model organisms such C.
elegans, zebrafish, Xenopus and mice, and combine animal work with stateof-
the art molecular biology and imaging studies. The candidates should have
excellent communication and team skills, be fluent in either German or
English, and be enthusiastic about applying cutting edge molecular and developmental
biology to address medical problems and their therapies.

The position is immediately available for a period of 2-6 years.
Salary according to E13 (postdoc) and E13/2 (PhD student).
Further information can be found at http://www.nephrolab.org
Applications (English/German), including a full CV, summary of the master/
diploma thesis, and name and address of two references, should be submitted
by mail or e-mail to:

Prof. Dr. Gerd Walz
Universitaetsklinikum Freiburg
Medizinische Klinik IV- Nephrologie/Allgemeinmedizin
Hugstetterstrasse 55
79106 Freiburg
Tel +49 761 270-3251
Fax -3245,
gerd.walz@uniklinik-freiburg.de.

Please add the internal reference number 4906 to your application.

Deadline for admission is July 31, 2008


The GSfBS will provide you with an excellent scientific environment
and an outstanding curriculum for your doctorate. Faculty members
listed below do research in molecular genetics, functional genomics,
cell biology, evolutionary biology, biotechnology and biochemistry in
a variety of model organisms. Details of the training and research
programme can be found on the website. We invite you to apply for
a position in the graduate school in Cologne, the exciting city in the
heart of Europe.

For further information please visit our web site at:

http://www.gs-biosciences.uni-koeln.de/gsfbs_start.html

Contact:

Dr. Isabell Witt
Graduate School for Biological Sciences,
Zülpicher Strasse 47,
50674 Cologne
Germany.

E-mail: isabell.witt@uni-koeln.de
Tel: +49 (0)221 470 1683

Faculty
Marcel Bucher
Jürgen Dohmen
Ulf-Ingo Flügge
Ute Höcker
Thorsten Hoppe
Jonathan Howard
Martin Hülskamp
Reinhard Krämer
Christian Kubisch
Thomas Langer
Maria Leptin
Michael Melkonian
Carien Niessen
Siegfried Roth
Björn Schumacher
Günther Schwarz
Aleksandra Trifunovic
Mirka Uhlirova
Brunhilde Wirth

Applications are invited for a vacant PhD position (starting as soon as possible,
TVL13/2) to join a dynamic research group (Functional Genomics, headed
by Prof. Ulrike Müller) at the Institute for Pharmacy and Molecular Biotechnology
IPMB, University of Heidelberg.

Our research group is interested in the physiological and pathological function
of proteins involved in Alzheimer´s disease, in particular proteins of the
amyloid precursor protein APP gene family (e.g. Herms et al., The EMBO J.
23: 4106; Ring et al. J. Neuroscience, 27, 7817). Although APP and its metabolism
is central to the pathogenesis of Alzheimer´s disease the physiological
and normal cell biological functions of APP family proteins are poorly
understood. Current projects focus on the role of APP family proteins in the
nervous system including the generation, function and maintenance of synapses.
These studies will involve work with gene targeted mouse mutants
and cells derived from them that are studied by biochemical, cell biological
and immunocytochemical methods. Applicants should be highly motivated
and hold a degree in Neurobiology, Biology, Medicine or Biochemistry. Experience
in neurobiology, cell biology or biochemistry including the analysis of
transgenic mice are an advantage.

The University of Heidelberg strongly encourages qualified women scholars to apply.
Handicapped persons with the same equivalent qualifications will be given preference.
If interested please send a short application including CV, statement of research
experience and interests, publications and names of two referees to

u.mueller@urz.uni-hd.de
Prof. Ulrike Müller,
Institute for Pharmacy and Molecular Biotechnology IPMB
University of Heidelberg,
Im Neuenheimer Feld 364,
69120 Heidelberg

Tel: +49-6221-546717 (Büro), -5821 (Sekretariat)

http://www.uni-heidelberg.de/institute/fak14/ipmb/

Call for applications for a postdoctoral position, Call for applications for a postdoctoral position: immuneregulation in the CNS (TV-L equivalent to BATIIa) A postdoctoral position is currently available at the Clinical Research Group for MS and Neuroimmunology located at the University of Wuerzburg, Department of Neurology. We are looking for a creative and motivated postdoc with ambitious career interest and experience in immunology. The work is related to the fundamental mechanisms of immune regulation in the central nervous system, especially the role of novel coinhibitory molecules of the B7-family and the interaction of CNS-antigen-presenting relation with regulatory T cells. Approaches cover experimental animal models using conditional transgenes and ablatable systems as well as various techniques in human cellular and molecular immunology. The work is funded by the Deutsche Forschungsgemeinschaft DFG as part of the Sonderforschungsbereich 581 (Molecular models of nervous system diseases). Please send a letter of application including curriculum vitae, certificates and names and addresses of potential referees to: Heinz Wiendl, MD Professor of Neurology and Head of the Clinical Research Group for Multiple Sclerosis and Neuroimmunology Department of Neurology, University of Wuerzburg Josef-Schneider-Straße 11 97080 Wuerzburg Germany Tel.: + 49-931-201-23755 Fax.: + 49-931-201-23488 E-mail: heinz.wiendl@klinik.uni-wuerzburg.de Secretary for the Clinical Research Group for MS and Neuroimmunology Tel.: +49-9 31-2 01-2 37 56 Recent literature: Magnus T, Schreiner B, Korn T, Jack C, Hong G, Antel J, Ifergan I, Chen L, Bischof F, Bar-Or A, Wiendl H. Microglial expression of the B7-family member B7-H1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS. J Neuroscience 2005; 25(10):2537-2546 Feger U, Tolosa E, Huang Y, Waschbisch A, Biedermann T, Melms A, Wiendl H. HLA-G expression defines a novel regulatory T cell subset present in human peripheral blood and sites of inflammation. Blood. 2007; 110(2):568-77 Meuth SG, Bittner S, Meuth P, Simon OJ, Budde T, Wiendl H. TWIK-related acid sensitive K+ channel 1 (TASK1) and TASK3 critically influence T lymphocyte effector functions. J Biol Chem. 2008; Epub ahead of print Zozulya A, Wiendl H. Mechanisms of disease: the role of regulatory T cells and dendritic cells in Multiple sclerosis. Nature Reviews Clin Practice, In press Lafon M, Megret F, Meuth SG, Romero M, Lafage M, Chen L, Aleopoulou L, Flavell R, Prehaud C, Wiendl H. Detrimental contribution of the immunoinhibitor B7-H1 to rabies virus encephalitis. J Immunol. In press Ortler S, Leder C, Mittelbronn M, Zozulya A, Knolle P, Chen L, Kroner A, Wiendl H. B7-H1 modulates neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of Multiple sclerosis. Eur J Immunol. In press Kontakt: Prof. Dr. Heinz Wiendl (heinz.wiendl@klinik.uni-wuerzburg.de), Neurologische Klinik der Universität Würzburg, Josef-Schneider-Straße 11, 97080 Würzburg , Tel.: 0931-201-23756 , FAX: 0931-201-23488 URL: http://www.klinik.uni-wuerzburg.de/neurologie

The Center for Biochemistry and Molecular Cell Research (ZBMZ) at the Elite
University Freiburg is seeking for 3 Postdocs and 2 PhD Students in Apoptosis Research
in the groups of Prof. Dr. Christoph Borner and Dr. Ulrich Maurer

Topics for the postdocs:
• Role of cathepsins in apoptosis
• Function of a novel class of Bcl-2 family proteins (AG Maurer)
• Rebuilding apoptosis signaling in yeast (in the frame of the Center for
Biological Signalling Studies (bioss) funded by the Excellence Initiative)

Topics for the PhD students:
• Mechanisms of apoptosis induction by alphaviruses
• Mechanisms of FasL-induced apoptosis in primary mouse hepatocytes

Broad knowledge of biochemical, molecular and cellular biology is required, experience in mouse work is an advantage and genuine interest in an academic career is a must. We offer excellent working conditions in a stimulating scientific environment which includes the newly created Center of Biochemistry and Molecular Cell Research (ZBMZ), the Excellence Initiative funded Research Cluster bioss and the Spemann Graduate School of Biology and Medicine (SGBM) as well as access to central core facilities in proteomics, genomics, imaging and system
biology at the Center for Biosystems Analysis (ZBSA).

Applications include CV, publication list, motivation letter and names and contact
information of three references, and can be sent by e-mail or postal mail to:

Prof. Christoph Borner
Institute of Molecular Medicine, ZBMZ,
Stefan Meier Str. 17,
D-79104
Freiburg,
Germany,
christoph.borner@uniklinik-freiburg.de

For further informations see www.mol-med.uni-freiburg.de.

Closing date: May 15,2008.

Research and teaching at the graduate and postgraduate level is in English.

Link: http://www.laborjournal.de/rubric/markt/gesetzt/S_08_04_a44.pdf