The Center of Experimental Medicine, Institute of Tumor Biology invites applications for the post of Scientist (Postdoctoral Researcher).

The Center of Experimental Medicine, Institute of Tumor Biology invites applications for

the post of Scientist (Postdoctoral Researcher)

The initial contract is for three years (depending on the release of funds), and further
extension is possible. The position is vacant and the successful candidate can begin
immediately. The project “Detection of metastatic founder cells for stratification and
monitoring of systemic therapies in cancer patients” is funded by the Federal Ministry
of Education and Research and focuses on molecular diagnostics in cancer. The aim
of the project is to assess the biological potential of these cells in order to enable a
more precise prediction of the prognosis and to assess the need for adjuvant therapy
in individual cancer patients. The project leaders, Prof. Pantel and Prof. Burkhardt,
have profound experience in experimental and clinical studies on tumour dissemination
and cancer micro-metastasis (Nature Rev. Cancer 8, 329-340, 2008).

Job description: The successful applicant will work as part of an experienced team of
senior scientists and technicians and have the opportunity of working on the development
of a new diagnostic platform for the detection and molecular characterization of
metastating stem cells in cancer patients. There is the opportunity of building up a
research group which will be driven by the applicant’s innovative skills and commitment
to the project.

Profile: Applicants holding a PhD or MD/PhD in biology, biochemistry or medicine,
and who have profound knowledge in experimental medical research with a focus on
molecular biology and/or immunology should apply.

For further information, please contact Mrs Pakusa, Administrative Office, Institute for
Tumour Biology, phone: +49-40-428033503.

The University Medical Center Hamburg-Eppendorf appoints its personnel according to
eligibility, aptitude and professional skills. Disabled candidates will be given preference
in the case of equal qualifications. The University Medical Center Hamburg-Eppendorf
supports equal opportunities for women, and women are encouraged to apply.

Please send your full application until June 23rd, 2008 to the Universitätsklinikum
Hamburg-Eppendorf, GB Personal & Organisation, Frau Schild, PPO 5,
Kzf.: 2008-06/171; Martinistr. 52, 20246 Hamburg

International PhD Program Tübingen, Fall 2008 in The Max Planck Institute for Developmental Biology and the Friedrich Miescher Laboratory in Tübingen.

International PhD Program Tübingen, Fall 2008

The Max Planck Institute for Developmental Biology and the
Friedrich Miescher Laboratory in Tübingen, Germany, invite applications
for PhD positions in following areas:

Cell Biology
Developmental Genetics
Structural Biology
Quantitative Genetics
Plant Development
Evolutionary Biology

Highly qualified applicants from all countries are invited to apply. All
applicants must hold or anticipate to receive a Diploma or Masters
degree by the time of their start as a PhD student in our institutes.
Candidates have to be fluent in written and spoken English (GRE compulsory
for non European candidates). The positions are funded by
Max Planck Fellowships.

Application form, evaluation forms (2 needed) and all details about our
online registration are available at http://www.eb.tuebingen.mpg.de/

Application deadline is July 13, 2008.

After the review of completed
applications selected candidates will be invited for personal interviews
in Tübingen during September 3-5, 2008.

Postdoc/Junior Group Leader in Molecular Plant Sciences in University of Bonn,

The Institute of Cellular and Molecular Botany (IZMB, http://izmb.de)
University of Bonn, Germany, invites applications for the position as
Postdoc/Junior Group Leader in Molecular Plant Sciences
(wissenschaftlicher Mitarbeiter, paid according to E 13 TVL)

starting at October 1, 2008. Applicants must hold a PhD degree (Dr. rer.
nat.) in Botany/Plant Sciences, should have some post doc experience
(1-3 years), a good publication record and teaching experiences.
We seek a highly motivated and qualified person with a research focus
in either plant-microbe interaction, molecular plant physiology, plant
cell biology, or plant biotechnology. The successful candidate is expec -
ted to participate in the M.Sc. Plant Sciences degree programme with
a teaching obligation of 4SWS.

A laboratory with basic equipment for plant molecular and cell biological
work is available and additional equipment may be shared with the
other research groups in the institute. The junior group leader will be
supported by a part time technician, a student teaching assistant, and a
moderate budget to cover the most basic expenses. Additional thirdparty
fund sources will have to be developed by the successful candidate.
The initial contract runs for 3 years with the possibility of renewal for maximally
3 more years. The jobholder will be entitled to a local commuter
“Job-Ticket” available from the public utility company, Bonn.
The University of Bonn is an equal opportunities employer. Preference
will be given to suitably qualified women or handicapped people, all other
considerations being equal.

Applicants for the academic position are expected to submit a cover letter,
CV, list of publications, description of research activities/projects and
teaching experience, final grade certificates and names of three referees.
Please address your application to:

Managing Director
Institute of Cellular and Molecular Botany
University of Bonn
Kirschallee 1
D-53115 Bonn

The deadline for applications is July 1, 2008.

A group leader position and a postdoctoral position in the Department of Developmental Immunology.

A group leader position and a postdoctoral position
are available in the Department of Developmental Immunology.
Current research in the department focuses on the evolution of the adaptive
immune system and the development of the thymic microenvironment (See
our web-site at http://www.immunbio.mpg.de/home/research/immun/

Applicants for the group leader position should have completed internationally
recognized post-doctoral research and will be free to choose topics complementary
to the current activities in the department. Innovative research proposals
involving quantitative and/or synthetic approaches to the function of the
immune system or model organisms not yet represented in the department
are particularly welcome.

The group leader position is for an initial 5-year appointment with the
possibility of extension. Technical support and funds for one PhD student
or postdoctoral fellow plus consumables will be provided; applicants are
encouraged to obtain outside funding. Payment and social benefits will be
in accordance with the regulations of the German TVoeD (salary agreement
for public service employees). Group leaders have full access to the excellent
animal (zebrafish/mouse), cell sorting, sequencing and imaging facilities of
the institute.

Applicants for the post-doctoral post should have experience in molecular
biology/immunology and an excellent publication record. The post-doctoral
fellow is expected to work on aspects of the evolution of the immune system
using mice and flies as model systems. Previous experience in fly genetics
is welcome but not essential.

In order to increase the proportion of female staff members, applications
from female scientists are particularly encouraged. The Max-Planck Society
strives to offer more employment for the disabled. Disabled candidates are
encouraged to apply. A childcare facility is attached to the Institute. Parttime
employment is possible.

Applicants should send their CV, list of publications and a brief statement
of research plans and arrange for 3 reference letters to be sent with the
index number 020408 to the Max-Planck Institute of Immunobiology,
Personnel Department, Stuebeweg 51, D-79108 Freiburg, Germany
(weigold@immunbio.mpg.de). Informal inquiries should be directed to Thomas
Boehm (boehm@immunbio.mpg.de). Applications will be accepted until the
vacancy is filled.

1 PhD student /1 Postdoctoral Fellow in The Department of Nephrology at the University Hospital Freiburg.

We are extending our research group focused on the elucidation of signaling
pathways during renal development and disease, and offer PhD and postdoctoral
positions to qualified scientists with experience in molecular and/
or developmental biology. Highly motivated PhD students with a master/ diploma
degree in biology, biochemistry or related life sciences are welcome
to apply. The positions are immediately available at the Center for Clinical
Research / Molecular Nephrology (Director: Prof. Dr. Walz). As part of a
multidisciplinary team you will work closely with model organisms such C.
elegans, zebrafish, Xenopus and mice, and combine animal work with stateof-
the art molecular biology and imaging studies. The candidates should have
excellent communication and team skills, be fluent in either German or
English, and be enthusiastic about applying cutting edge molecular and developmental
biology to address medical problems and their therapies.

The position is immediately available for a period of 2-6 years.
Salary according to E13 (postdoc) and E13/2 (PhD student).
Further information can be found at http://www.nephrolab.org
Applications (English/German), including a full CV, summary of the master/
diploma thesis, and name and address of two references, should be submitted
by mail or e-mail to:

Prof. Dr. Gerd Walz
Universitaetsklinikum Freiburg
Medizinische Klinik IV- Nephrologie/Allgemeinmedizin
Hugstetterstrasse 55
79106 Freiburg
Tel +49 761 270-3251
Fax -3245,

Please add the internal reference number 4906 to your application.

10 Ph. D. studentships starting autumn 2008

Deadline for admission is July 31, 2008

The GSfBS will provide you with an excellent scientific environment
and an outstanding curriculum for your doctorate. Faculty members
listed below do research in molecular genetics, functional genomics,
cell biology, evolutionary biology, biotechnology and biochemistry in
a variety of model organisms. Details of the training and research
programme can be found on the website. We invite you to apply for
a position in the graduate school in Cologne, the exciting city in the
heart of Europe.

For further information please visit our web site at:



Dr. Isabell Witt
Graduate School for Biological Sciences,
Zülpicher Strasse 47,
50674 Cologne

E-mail: isabell.witt@uni-koeln.de
Tel: +49 (0)221 470 1683

Marcel Bucher
Jürgen Dohmen
Ulf-Ingo Flügge
Ute Höcker
Thorsten Hoppe
Jonathan Howard
Martin Hülskamp
Reinhard Krämer
Christian Kubisch
Thomas Langer
Maria Leptin
Michael Melkonian
Carien Niessen
Siegfried Roth
Björn Schumacher
Günther Schwarz
Aleksandra Trifunovic
Mirka Uhlirova
Brunhilde Wirth

PhD in Neurobiology/Functional Genomics at University of Heidelberg.

Applications are invited for a vacant PhD position (starting as soon as possible,
TVL13/2) to join a dynamic research group (Functional Genomics, headed
by Prof. Ulrike Müller) at the Institute for Pharmacy and Molecular Biotechnology
IPMB, University of Heidelberg.

Our research group is interested in the physiological and pathological function
of proteins involved in Alzheimer´s disease, in particular proteins of the
amyloid precursor protein APP gene family (e.g. Herms et al., The EMBO J.
23: 4106; Ring et al. J. Neuroscience, 27, 7817). Although APP and its metabolism
is central to the pathogenesis of Alzheimer´s disease the physiological
and normal cell biological functions of APP family proteins are poorly
understood. Current projects focus on the role of APP family proteins in the
nervous system including the generation, function and maintenance of synapses.
These studies will involve work with gene targeted mouse mutants
and cells derived from them that are studied by biochemical, cell biological
and immunocytochemical methods. Applicants should be highly motivated
and hold a degree in Neurobiology, Biology, Medicine or Biochemistry. Experience
in neurobiology, cell biology or biochemistry including the analysis of
transgenic mice are an advantage.

The University of Heidelberg strongly encourages qualified women scholars to apply.
Handicapped persons with the same equivalent qualifications will be given preference.
If interested please send a short application including CV, statement of research
experience and interests, publications and names of two referees to

Prof. Ulrike Müller,
Institute for Pharmacy and Molecular Biotechnology IPMB
University of Heidelberg,
Im Neuenheimer Feld 364,
69120 Heidelberg

Tel: +49-6221-546717 (Büro), -5821 (Sekretariat)


A postdoctoral position is currently available at the Clinical Research Group for MS and Neuroimmunology located at the University of Wuerzburg

Call for applications for a postdoctoral position, Call for applications for a postdoctoral position: immuneregulation in the CNS (TV-L equivalent to BATIIa)

A postdoctoral position is currently available at the Clinical Research Group for MS and Neuroimmunology located at the University of Wuerzburg, Department of Neurology. We are looking for a creative and motivated postdoc with ambitious career interest and experience in immunology.
The work is related to the fundamental mechanisms of immune regulation in the central nervous system, especially the role of novel coinhibitory molecules of the B7-family and the interaction of CNS-antigen-presenting relation with regulatory T cells. Approaches cover experimental animal models using conditional transgenes and ablatable systems as well as various techniques in human cellular and molecular immunology.
The work is funded by the Deutsche Forschungsgemeinschaft DFG as part of the Sonderforschungsbereich 581 (Molecular models of nervous system diseases). Please send a letter of application including curriculum vitae, certificates and names and addresses of potential referees to:

Heinz Wiendl, MD
Professor of Neurology and Head of the Clinical Research Group for Multiple Sclerosis and Neuroimmunology
Department of Neurology, University of Wuerzburg
Josef-Schneider-Straße 11
97080 Wuerzburg
Tel.: + 49-931-201-23755
Fax.: + 49-931-201-23488
E-mail: heinz.wiendl@klinik.uni-wuerzburg.de

Secretary for the Clinical Research Group for MS and Neuroimmunology
Tel.: +49-9 31-2 01-2 37 56

Recent literature:

Magnus T, Schreiner B, Korn T, Jack C, Hong G, Antel J, Ifergan I, Chen L, Bischof F, Bar-Or A, Wiendl H. Microglial expression of the B7-family member B7-H1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS. J Neuroscience 2005; 25(10):2537-2546
Feger U, Tolosa E, Huang Y, Waschbisch A, Biedermann T, Melms A, Wiendl H. HLA-G expression defines a novel regulatory T cell subset present in human peripheral blood and sites of inflammation. Blood. 2007; 110(2):568-77
Meuth SG, Bittner S, Meuth P, Simon OJ, Budde T, Wiendl H. TWIK-related acid sensitive K+ channel 1 (TASK1) and TASK3 critically influence T lymphocyte effector functions. J Biol Chem. 2008; Epub ahead of print
Zozulya A, Wiendl H. Mechanisms of disease: the role of regulatory T cells and dendritic cells in Multiple sclerosis. Nature Reviews Clin Practice, In press
Lafon M, Megret F, Meuth SG, Romero M, Lafage M, Chen L, Aleopoulou L, Flavell R, Prehaud C, Wiendl H. Detrimental contribution of the immunoinhibitor B7-H1 to rabies virus encephalitis. J Immunol. In press
Ortler S, Leder C, Mittelbronn M, Zozulya A, Knolle P, Chen L, Kroner A, Wiendl H. B7-H1 modulates neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of Multiple sclerosis. Eur J Immunol. In press

Kontakt: Prof. Dr. Heinz Wiendl (heinz.wiendl@klinik.uni-wuerzburg.de), Neurologische Klinik der Universität Würzburg, Josef-Schneider-Straße 11, 97080 Würzburg , Tel.: 0931-201-23756 , FAX: 0931-201-23488
URL: http://www.klinik.uni-wuerzburg.de/neurologie