The research group on “Gene Therapy & Virotherapy“ University Clinic Tübingen, Germany (Prof. Dr. U. M. Lauer/Prof. Dr. M. Bitzer) invite applications for a Postdoctoral Position being funded by the Federal Ministry of Education and Research (BMBF).


This position is embedded into the research program of the German Oncolysis
Consortium (GOC) being headed by Prof. Lauer. GOC is dedicated to
the clinical introduction of safety and efficiency engineered state-of-the-art
virotherapeutics.

Areas of research:
- Generation and production of different oncolytic viral vectors encoding efficiency-
improved suicide genes under a protease-restricted tumor tropism
- Preclinical characterization of these vectors on tumor cell cultures, primary
cells, in animal models as well as in tissue cultures gained from resection
pieces of cancer patients undergoing surgical tumor resections (Int J Oncol
2009; 34:1247-1256)
- Development and employment of detection systems enabling a precise in
vivo monitoring of vector replication in individual patients
- Characterization of the genetic stability of our novel vectors, the stability of
the attenuation properties and the ability of mobilization of important vector
elements.

Prerequisites:
Applicants must have a Ph.D. or M.D. degree. A strong background in molecular
virology, virotherapy, cell & cancer biology, and biotechnology will be of
advantage. Women are especially requested to make an application. We give
priority to applicants with a disability and essentially equal qualifications.

Starting date:
The position (E13/TV-L) is available from September 1; later starting dates are also possible.
Duration: Initially for 3 years with an option for extension.

Apply to:
Prof. U.M. Lauer,
University Clinic Tübingen,
Otfried-Müller-Str. 10, D-72076
Tübingen, Germany;

phone: +49-7071-2983190;
fax: +49-7071-294686.
Please send your application (including CV, list of publications, 2-3 references)
preferentially by e-mail: ulrich.lauer@uni-tuebingen.de.