Ph.D. position in Bacterial Genetics in Köln

In frame of a DFG-funded project a Ph.D. position (1/2 E13 TV-L) is available to study mechanisms controlling transcriptional silencing by the global regulator and nucleoid-associated protein H-NS in Escherichia coli, and to elucidate the role of LuxR-type transcription factors in antagonistic control of H-NS in response the stress conditions and environmental stimuli. Experience in bacterial genetics and/or microbiology as well as knowledge of standard molecular and biochemical techniques is advantageous. Applicants should hold a Diploma or Masters-Degree in Biology or Biochemistry. Applicants are requested to send a curriculum vitae, a statement of interest, correspondence addresses of two referees by August, 20 2009 (preferably by email). The University of Cologne is an equal opportunity employer in compliance with German disability laws. Applications from women and disabled persons are particularly welcome.


Prof. Dr. Karin Schnetz

Institut für Genetik, Universität zu Köln
Zülpicher Str. 47
50674 Köln

Postdoc in Institute for Medical Microbiology and Hygiene Universitätsklinikum Tübingen

At the Institute for Medical Microbiology and Hygiene is now the site of one researcher / scientist (Postdoc, E13) for first 2 years to fill. Our team is working on the infection biology of enteropathogenen bacteria (Yersinia enterocolitica).

Research focuses on questions about the pathogen-host interaction (Type III Sekretionssystem, outer membrane proteins of the pathogen Immunevasionsstrategien) methods are the focus of infection immunology, molecular biology and cellular Mirobiologie. We are looking for a (n) highly motivated (s) colleague (or research scientists experienced physicians), who a lot of commitment and initiative in projects of the working group and engage in interdisciplinary teamwork is interested. Relevant experience with immunological, molecular biological, genetic and cellular-microbiological methods are highly desirable.

Applications including CV, publication list, two reference letters as well as details of previous and current research area and the range of methods, or questions to the position and the working group,

please contact:
Prof. Dr. Ingo B. Autenrieth
Institute for Medical Microbiology and Hygiene Universitätsklinikum Tübingen
Elfriede-Aulhorn-Str. 6 72076 Tübingen
ingo.autenrieth @ med.uni-tuebingen.de


Prof. Dr. Ingo B. Autenrieth

Institut für Med. Mikrobiologie und Hygiene
Elfriede-Aulhorn-Str. 6
72076 Tübingen

Tel.: 07071 29 82351
Fax: 07071 29 5440,07071 29 5440

Scientist Neuropharmacology (PET ligand discovery and development)

Who we are
At Roche, 80,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity, and on seeing each other’s differences as an advantage. To innovate healthcare, Roche has ambitious plans to keep learning and growing – and is seeking people who have the same goals for themselves.

The headquarters in Basel is one of Roche’s largest sites. It is home to the Corporate Executive Committee, the Pharmaceuticals and Diagnostics Divisions and the global business functions. Roche Basel also covers the entire business chain from research, development and production through to marketing. Over 8,000 people from more than 60 countries work at the site.

The Position
You will direct a laboratory focused on the in vitro and in vivo pharmacological characterization of novel radiotracers for positron emission tomography (PET). In part, this entails supporting drug discovery projects by measuring receptor occupancy of new drug candidates in rodents. In collaboration with medicinal chemists, radiochemists and drug discovery teams, you will identify and characterize candidate tracers and coordinate their development in external PET centers. This effort will be integrated within a multidisciplinary group focused on the development of novel PET radiotracers. In addition, you will act
as a key contact person for drug discovery teams and will actively participate in defining their neuroimaging strategy. As a member of project teams, you will directly interact with project leaders and senior-level scientists.

Who you are
You’re someone who wants to influence your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies, and where a job title is not considered the final definition of who you are, but the starting point. You have a Ph.D. or equivalent university degree in the neurosciences with a strong focus in neuropharmacology and neuroanatomy. In addition, you have proven experience in preclinical drug discovery and development. You have an excellent understanding of the principles that regulate drug activity in animals and humans (e.g., pharmacokinetics, metabolism, brain penetration and receptor kinetics). Also, experience with autoradiography or other morphological techniques is necessary. Excellent command of spoken and written English is advantageous.

Job ID No.: 12297
Contact HR: S. Chapanduka,
Phone: +41 61 688 66 03

Contact Line: E. Borroni,
Phone: +41 61 688 42 48
The next step is yours. To apply online today or learn about other exciting positions, please visit http://careers.roche.com

PhD Molecular Immunology at the Hospital of the Ludwig-Maximilians University in Munich

In the Department of Rheumatology (Arthritis Unit) of the Hospital of the Ludwig-Maximilians University in Munich is now a doctoral thesis on molecular mechanisms of immune regulation at the moment. The project deals with the emergence of regulatory T cells and analysis of the molecular mechanisms of their generation. It is supported by the DFG via the Graduiertenkolleg 1202 (oligonucleotides) at the Klinikum der LMU encouraged. The Arthritis Unit has a 2007 new set of molecular biological research laboratory with spacious work areas and a complete infrastructure for all the work and methods of modern molecular biology laboratories working. The scientific projects of the unit will include Rheumatism by the DFG (Schu 786/8-1 individual applications, Schu 786/2-5, SK59/4-1; Graduiertenkolleg 1202, SFB 571 Mechanisms of auto-immunity) and the industry. As part of the work is to promote interaction with other sub-projects of the graduate program at the site and the active SFBs planned.


Prof. Dr. med. Hendrik Schulze-Koops

Rheumaeinheit, Medizinische Poliklinik, Universität München
Pettenkoferstraße 8a
80336 München

Tel.: 089 5160 3579
Fax: 089 5160 4199,089 5160 4199

Postdoc / PhD student: Tumor Stem Cell Research in Freiburg

The Section of Molecular Oncology at the Clinic for Radiation Medicine of the University Hospital Freiburg, looking for a postdoc and a n / e doctoral candidates in order to strengthen our team we are looking for two highly motivated employees. Research focus is the role of tumor stem cells for tumor resistance to established therapies and the development of new tumor-specific stem cell therapy procedures. Requirements: strong commitment and willingness on animal research (Tumorxenograft mouse models). Experience in cell culture, flow cytometry, standard cell and molecular biological techniques are advantageous but not essential. The posts are initially for 2 or 3 years with option for renewal.

Please apply with the usual documents at the following address: Prof. Dr. Gabriele Niedermann, Clinic for Radiation Medicine, Robert-Koch-Str. 3, 79106 Freiburg. For more information phone 0761-270-9514 or e-mail gabriele.niedermann @ uniklinik-freiburg.de

Prof. Dr. med. Gabriele Niedermann (gabriele.niedermann@uniklinik-freiburg.de)

Klinik für Strahlenheilkunde
Robert-Koch-Str. 3
79106 Freiburg

Tel.: 0761-270-9514
Fax: 0761-270-9513,0761-270-9513