10 Fellowships, 3-year Ph.D. Programme starting fall 2009 from Cologne International Graduate School

Cologne International Graduate School

From Embryo to Old Age

10 Fellowships, 3-year Ph.D. Programme starting fall 2009

The University of Cologne has a long-standing tradition and
world-wide reputation of top-level molecular biological research.
Beginning in the winter semester 2009/2010 the Research School
in Biology (From embryo to old age: the cell biology and genetics
of health and disease) will be offering a high-level Ph.D. programme
for students with excellent qualifications. The participating
research groups use today's preeminent microbial, plant
and animal model systems to investigate cell biological and
genetic mechanisms whose perturbation during the life cycle of
an organism results in disease.

The three-year programme starts with a six-month rotation and
course period, followed by a PhD project in one of the participating
groups. Seminars and training courses complement the research
work. Comprehensive support is provided throughout the programme.
The programme language is English, and no tuitions

10 competitive three-year fellowships (initially 1000 EUR, then
1300 EUR per month) are available. In addition, up to 10 students
with self-provided funding may be selected as associates.

We invite you to apply to the IGSDHD in Cologne, the exciting city
in the heart of Europe.

To obtain further information please visit our website at:
Complete Applications for fall 2009 are accepted until
March 31, 2009

Candidates from Countries with no Visa requirement can apply
until April 25, 2009

Dr. Isabell Witt, IGSDHD
Zuelpicher Strasse 47
D-50674, Cologne

Phone: +49(0)221 4701683
Fax: +49(0) 4701632,

3 PhD student positions

Analysis of synaptic function and small neuronal networks in Caenorhabditis elegans

8th January 2009

Up to 3 positions for PhD students are available immediately in the Gottschalk lab at the Goethe-University Frankfurt, Institute of Biochemistry, for up to three years. The projects are funded by the DFG, HFSPO, Cluster of Excellence Frankfurt and the Schram-Foundation:

1) Novel pre-synaptic proteins acting in neurotransmission will be uncovered by co-purification with synaptic neurotransmitter vesicles, and by reverse genetic screening, utilizing new methods for optical stimulation of neurons (optogenetics) that we developed. Proteins will be functionally characterized by molecular and cell biology, genetics and electrophysiology.

2) Similarly, post-synaptic proteins that we purified and showed to interact with nicotinic acetylcholine receptors will be functionally characterized.

3) Small neuronal networks will be analyzed by optogenetic activation (via Channelrhodopsin-2) or inhibition (via Halorhodopsin), and assaying evoked behavioural or network effects, using automated video analysis, Ca2+ imaging and electrophysiology.

For further information, see lab publications (EMBO J (2005) 24: 2566; Curr. Biol. (2005) 15: 2279; EMBO J (2007) 26: 4313; Nature (2007) 446: 633; Nat. Meth. (2008) 5: 895; PNAS (2008) 105: 16350; MBC (2008) online 10.1091/mbc.E08-08-0851).

A diploma or masters degree in Biochemistry, Biology or Chemistry is required. Candidates must have a strong background and interest in the function of the nervous system, and solid experience in molecular biology, biochemistry and cell biology; programming skills (Matlab, LabView) are desired. Knowledge of C. elegans biology and techniques is mostly welcome, but no strict necessity. Please send applications containing the usual documents, CV, short description of research experience and interests, and references to:

Alexander Gottschalk, PhD, Juniorprofessor
Goethe-Universität Frankfurt
Institute for Biochemistry, Biocenter N220
Max-von-Laue Strasse 9
D-60438 Frankfurt
e-mail: a.gottschalk@em.uni-frankfurt.de

Post-doctoral position at the Hannover Medical School

Post-doctoral position at the Hannover Medical School, Department of Hematology, Hemostasiology, Oncology and Stem Cell Transplantation, Laboratory for Lymphatic Cell Therapy Rebirth Excellence Cluster

Prof Dr. Stripecke (www.stripecke-lab.de)

Main task:

Establishment of immunologic assays to evaluate genetically engineered cellular vaccines in tumor and infectious diseases models.

Specific requirements:
PhD or MD/PhD title obtained within last 3 years and strong publication record. Candidates should have demonstrated solid previous experience with ex vivo culture of mouse/human dendritic cells and T cells, immunologic assays (T cell proliferation, CTL/ Th cytokine profile characterization, ELISPOT), analytical flow cytometry and histologic analyses. Previous experience with molecular biology techniques and tumor and infectious disease models are desirable. Experience with lentiviral vector production and testing is a plus.

Expected skills:
Inititative, responsibility, team-work, fluency (verbal and written) in English, strong computer skills for data analyses and presentation. Competence in supervision of students and technicians and excellent organizational skills.
This full-time position is for one year, desirable start date March 1st 2009, with possibility of renewals. Salary ranking is commensurate with qualifications (E12-E13).

Please send full Curriculum Vitae with three references to:

Prof. Dr. Renata Stripecke
Abteilung Haematologie OE 6860
Medizinische Hochschule Hannover
Carl Neuberg Strasse 1
30625 Hannover
E-Mail: Stripecke.Renata@mh-hannover.de.
Phone: ++49 (0) 511 532 6999