Scientist Neuropharmacology (PET ligand discovery and development)

Who we are
At Roche, 80,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity, and on seeing each other’s differences as an advantage. To innovate healthcare, Roche has ambitious plans to keep learning and growing – and is seeking people who have the same goals for themselves.

The headquarters in Basel is one of Roche’s largest sites. It is home to the Corporate Executive Committee, the Pharmaceuticals and Diagnostics Divisions and the global business functions. Roche Basel also covers the entire business chain from research, development and production through to marketing. Over 8,000 people from more than 60 countries work at the site.

The Position
You will direct a laboratory focused on the in vitro and in vivo pharmacological characterization of novel radiotracers for positron emission tomography (PET). In part, this entails supporting drug discovery projects by measuring receptor occupancy of new drug candidates in rodents. In collaboration with medicinal chemists, radiochemists and drug discovery teams, you will identify and characterize candidate tracers and coordinate their development in external PET centers. This effort will be integrated within a multidisciplinary group focused on the development of novel PET radiotracers. In addition, you will act
as a key contact person for drug discovery teams and will actively participate in defining their neuroimaging strategy. As a member of project teams, you will directly interact with project leaders and senior-level scientists.

Who you are
You’re someone who wants to influence your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies, and where a job title is not considered the final definition of who you are, but the starting point. You have a Ph.D. or equivalent university degree in the neurosciences with a strong focus in neuropharmacology and neuroanatomy. In addition, you have proven experience in preclinical drug discovery and development. You have an excellent understanding of the principles that regulate drug activity in animals and humans (e.g., pharmacokinetics, metabolism, brain penetration and receptor kinetics). Also, experience with autoradiography or other morphological techniques is necessary. Excellent command of spoken and written English is advantageous.

Job ID No.: 12297
Contact HR: S. Chapanduka,
Phone: +41 61 688 66 03

Contact Line: E. Borroni,
Phone: +41 61 688 42 48
The next step is yours. To apply online today or learn about other exciting positions, please visit http://careers.roche.com