The HZI, the Helmholtz Centre for Infection Research (www.helmholtz-hzi.de), seeks an experienced

Postdoctoral Research Scientist (Immunology)

for the Department of Vaccinology and Applied Microbiology to establish a
program to elucidate the mechanisms of action of mucosal adjuvants spinning
from our discovery pipeline, as well as the contribution of accessory cells and
the underlying mechanisms of cross talk between epithelial and immune cells.
The candidate must hold a PhD or equivalent in the area of immunology, documented
by publications. Expertise in the areas of memory, homing, signal
transduction or mucosal immunity will be considered as an advantage.
The Department has access to state of the art facilities for animal studies (SPF
up to BSL3), nucleic acid arrays platform, flow cytometry/sorting unit,
proteomics, NMR/mass spectrometry, and imaging (confocal, FESEM/TEM
and in vivo imaging).

Duration: The position is available for two years.
Starting date: The position is available immediately.
Salary: TVöD E13 + supplemented to E14

Informal inquiries should be directed to
Prof. Dr. Carlos A. Guzmán,
Phone: +49-531-61814600;
e-mail: carlos.guzman@helmholtz-hzi.de.

The Department of Molecular Membrane Biology has several openings for
Post-doctoral associates to work on the production, purification, and characterisation of selected

• G-protein coupled receptors (GPCRs) and their functional complexes
and subsequent crystallization of these membrane proteins for structure
determination by X-ray crystallography.

Applications, including the names of two referees, should be sent, preferably
electronically (secretariat.michel@mpibp-frankfurt.mpg.de), to:

Prof. Dr. Hartmut Michel
Max Planck Institute of Biophysics
Max-von-Laue-Str. 3
60438 Frankfurt am Main
Germany

The Max Planck Society is an equal opportunity employer,
and particularly encourages female applicants. It also tries to
increase the proportion of scientists with physical disabilities.
Respective applications are welcome.

Cologne International Graduate School

From Embryo to Old Age

10 Fellowships, 3-year Ph.D. Programme starting fall 2009

The University of Cologne has a long-standing tradition and
world-wide reputation of top-level molecular biological research.
Beginning in the winter semester 2009/2010 the Research School
in Biology (From embryo to old age: the cell biology and genetics
of health and disease) will be offering a high-level Ph.D. programme
for students with excellent qualifications. The participating
research groups use today's preeminent microbial, plant
and animal model systems to investigate cell biological and
genetic mechanisms whose perturbation during the life cycle of
an organism results in disease.

The three-year programme starts with a six-month rotation and
course period, followed by a PhD project in one of the participating
groups. Seminars and training courses complement the research
work. Comprehensive support is provided throughout the programme.
The programme language is English, and no tuitions
apply.

10 competitive three-year fellowships (initially 1000 EUR, then
1300 EUR per month) are available. In addition, up to 10 students
with self-provided funding may be selected as associates.

We invite you to apply to the IGSDHD in Cologne, the exciting city
in the heart of Europe.

To obtain further information please visit our website at:
http://www.uni-koeln.de/bio-graduateschool/index.html
Complete Applications for fall 2009 are accepted until
March 31, 2009

Candidates from Countries with no Visa requirement can apply
until April 25, 2009

Contact:
Dr. Isabell Witt, IGSDHD
Zuelpicher Strasse 47
D-50674, Cologne

Phone: +49(0)221 4701683
Fax: +49(0) 4701632,
isabell.witt@uni-koeln.de

Analysis of synaptic function and small neuronal networks in Caenorhabditis elegans

8th January 2009

Up to 3 positions for PhD students are available immediately in the Gottschalk lab at the Goethe-University Frankfurt, Institute of Biochemistry, for up to three years. The projects are funded by the DFG, HFSPO, Cluster of Excellence Frankfurt and the Schram-Foundation:

1) Novel pre-synaptic proteins acting in neurotransmission will be uncovered by co-purification with synaptic neurotransmitter vesicles, and by reverse genetic screening, utilizing new methods for optical stimulation of neurons (optogenetics) that we developed. Proteins will be functionally characterized by molecular and cell biology, genetics and electrophysiology.

2) Similarly, post-synaptic proteins that we purified and showed to interact with nicotinic acetylcholine receptors will be functionally characterized.

3) Small neuronal networks will be analyzed by optogenetic activation (via Channelrhodopsin-2) or inhibition (via Halorhodopsin), and assaying evoked behavioural or network effects, using automated video analysis, Ca2+ imaging and electrophysiology.

For further information, see lab publications (EMBO J (2005) 24: 2566; Curr. Biol. (2005) 15: 2279; EMBO J (2007) 26: 4313; Nature (2007) 446: 633; Nat. Meth. (2008) 5: 895; PNAS (2008) 105: 16350; MBC (2008) online 10.1091/mbc.E08-08-0851).

A diploma or masters degree in Biochemistry, Biology or Chemistry is required. Candidates must have a strong background and interest in the function of the nervous system, and solid experience in molecular biology, biochemistry and cell biology; programming skills (Matlab, LabView) are desired. Knowledge of C. elegans biology and techniques is mostly welcome, but no strict necessity. Please send applications containing the usual documents, CV, short description of research experience and interests, and references to:

Alexander Gottschalk, PhD, Juniorprofessor
Goethe-Universität Frankfurt
Institute for Biochemistry, Biocenter N220
Max-von-Laue Strasse 9
D-60438 Frankfurt
Germany
e-mail: a.gottschalk@em.uni-frankfurt.de

Post-doctoral position at the Hannover Medical School, Department of Hematology, Hemostasiology, Oncology and Stem Cell Transplantation, Laboratory for Lymphatic Cell Therapy Rebirth Excellence Cluster


Prof Dr. Stripecke (www.stripecke-lab.de)


Main task:
Establishment of immunologic assays to evaluate genetically engineered cellular vaccines in tumor and infectious diseases models.

Specific requirements:
PhD or MD/PhD title obtained within last 3 years and strong publication record. Candidates should have demonstrated solid previous experience with ex vivo culture of mouse/human dendritic cells and T cells, immunologic assays (T cell proliferation, CTL/ Th cytokine profile characterization, ELISPOT), analytical flow cytometry and histologic analyses. Previous experience with molecular biology techniques and tumor and infectious disease models are desirable. Experience with lentiviral vector production and testing is a plus.

Expected skills:
Inititative, responsibility, team-work, fluency (verbal and written) in English, strong computer skills for data analyses and presentation. Competence in supervision of students and technicians and excellent organizational skills.
This full-time position is for one year, desirable start date March 1st 2009, with possibility of renewals. Salary ranking is commensurate with qualifications (E12-E13).

Please send full Curriculum Vitae with three references to:

Prof. Dr. Renata Stripecke
Abteilung Haematologie OE 6860
Medizinische Hochschule Hannover
Carl Neuberg Strasse 1
30625 Hannover
GERMANY
E-Mail: Stripecke.Renata@mh-hannover.de.
Phone: ++49 (0) 511 532 6999

The Jena School for Microbial Communication (JSMC) is funded by the German Excellence Initiative. It conceptionally combines different research areas (microbial communities, interactions with plant, animal and human hosts and environmental interactions) to a comprehensive picture of microbial communication (www.jsmc.uni-jena.de). JSMC is an ambitious Graduate School prospectively comprising 150 PhD students who will be educated in a structured, interdisciplinary training program based on top-level fundamental research. Four faculties of the Friedrich Schiller University Jena, six non-university research institutions as well as twelve partner companies are participating in this cutting edge research and training program which includes an innovative PhD program, career development and intensive sociocultural care. Three embedded existing Research Training Groups as well as twelve other cooperative research projects are engaged to incorporate novel research areas to achieve a complete view of microbial communication.

We invite applications for
9 PhD Fellowships.

The positions are immediately available.


We expect:

* an equivalent of a Master’s degree in Natural or Life Sciences (e.g. Biology, Earth Sciences, Chemistry, Physics, Bioinformatics, or Medicine). Candidates about to earn their degree are welcome to apply.
* high motivation and interest to join one of the interdisciplinary research areas of JSMC
* creativity and interest to shape your own thesis project
* an integrative and cooperative personality
* very good communication skills in English


We offer:

* a top-level research environment
* a PhD stipend paid according to the rules of the DFG (German Research Foundation) as well as generous research funding
* a periodic research report system
* efficient supervision by a team of two supervisors
* a comprehensive mentoring program
* courses in novel technologies and soft skills
* a highly communicative atmosphere between the involved institutions and companies
* Jena - the German City of Science 2008: a young and lively city with dynamic business activities, successful scientific centers of innovation and a vibrant cultural scene around the famous Friedrich Schiller University


Friedrich Schiller University Jena is an equal opportunity employer.

For the first step of the application procedure please aquaint yourself with the scientific themes offered on our website

www.jsmc.uni-jena.de

and thoroughly fill in the "Statement of Interest" downloadable from this site. The application procedure is handled online exclusively via the JSMC website. Applications can only be considered upon receipt of the completed "Statement of Interest" form submitted to JSMC@uni-jena.deThis e-mail address is being protected from spam bots, you need JavaScript enabled to view it .

Deadline for submission of the completed “Statement of Interest” form: October 6th, 2008.

Successful applicants will be invited to attend the JSMC Recruitment Meeting in December 2008.