As a modern, maximum care hospital, we are among the leading University hospitals in Germany. Our 6,800 employees offer more than 59 powerful hospitals, specialized centers and institutes an optimal Patient care and professional education and training. With
approximately 1,300 beds, we are one of the largest hospitals in the region. Our international reputation stems from the interplay of high medical with the fulfillment of academic responsibilities in research and teaching.

The Institute of Genetics, University of Cologne, Department of Mouse Genetics and metabolism, Prof. Dr. Jens C. Brüning, seeking, Expiration to 30.06.2011 (with possibility of extension up to 30.06.2013) and, in part, within the framework of the SFB 832 "Molecular Basis and modulation of cellular Interactions in the Tumor Micro environment "PhD Student / Doctoral.

The project deals with the generation of a Luciferase Reporter Mouse and the Establishment of imaging methods for the analysis of the tumor micro-environment. Experience with methods of modern mouse genetics, working with cell cultures and molecular biological techniques are required, as well very good knowledge of English.

The classification is based on grade 13 of the TV-L. The Board of the University Hospital of Cologne, the women aim. For the proportion of women in this field to increase, applications are warmly welcomed by women and for equal suitability, qualifications and preferred professional performance, unless the person of a Competitor lying reasons predominate.

Applications from severely disabled people are welcome and are equally qualified preferred.
The work area is to be occupied with part-time staff in principle suitable.

For telephone information please contact
Dr. Lichtenberg by calling (0221) 470-3410 is available.

For more information visit: http://www.genetik.uni-koeln.de/

Have we awakened your interest? Then send your meaningful and
Please complete application until 31.07.2009 preferred by e-mail summary
in a pdf file at: u.lichtenberg@uni-koeln.de

or on the Post to:
Institute of Genetics, University of Cologne
Dr. Ursula Lichtenberg
Tender No.: e152
Zülpicher Str 47, 50674 Cologne

University of Würzburg Postdoctoral position

A postdoctoral position is available within the CRU216
„Characterization of the Oncogenic Signaling Network in Multiple Myeloma:
Development of Targeted Therapies“ (supported by the DFG)

Institute: Institute for Virology and Immunobiology,
Department of Immunology (chair: Prof. Dr. T. Hünig)
Location: Würzburg, Bavaria, Germany
Duration: 3 years (starting July 1st, 2009)

Summary of the project: Despite the fact that CD28 is predominantly expressed on aggressive variants of MM, little is known about the signaling network of CD28 in these cells. In the current project, we will examine the influence of CD28 signals on human MM cell lines and primary MM samples. Additionally, in a transgenic mouse
model closely recapitulating features of human MM, we will study the
role of CD28 in proliferation, differentiation and homing.
Person to contact: Interested candidates are invited to send their CV
and a summary of their latest research to: PD Dr. Ingolf Berberich
(berberich.i@uni-wuerzburg.de, phone: +49 931 201 49 930). Please
include the phone numbers and email addresses of 2 referees.

The University of Würzburg seeks to increase the number of women in
those areas where they are underrepresented and therefore explicitly
encourages applications from female scientists. The University of Würzburg
is an equal opportunity employer and will give preference to disabled
candidates having the same qualifications as their competitors.

The research group “Modelling and Imaging Pancreatic Cancer using
Conditional Mouse Models” (Head: Dr. Jens Siveke) in the II. Medical
Department at the Klinikum rechts der Isar (Gastroenterology) of the
Technical University of Munich invites applications for

a Postdoctoral Position (f/m) and a PhD Position (f/m)

Area of research: Our group is studying the biology of pancreatic diseases and in particular pancreatic cancer using conditional mouse models. For this project (“Evaluation of therapeutic strategies and monitoring through multi modal imaging in genetically engineered mice with endogenous pancreatic cancer“) within the newly formed SFB 824 “Imaging for the Selection,
Monitoring and Individualisation of Cancer Therapy” we are particularly interested in studying multimodal imaging such as MRT and PET as well as molecular imaging during development and therapy of pancreatic cancer in complex mouse models. Our interdisciplinary approach ranges from mouse genetics and molecular medicine to applying therapeutic studies in a preclinical setting using multiple imaging modalities.

Key References:

Siveke JT, Einwächter H, Lubeseder-Martellato C, Sipos B, Klöppel G,
Schmid RM. Concomitant pancreatic activation of KrasG12D and Tgfa
results in cystic papillary neoplasms reminiscent of human IPMN. Cancer
Cell. 2007;12:266-279.

Siveke JT, Schmid RM. Chromosomal instability in mouse metastatic pancreatic
cancer--it's Kras and Tp53 after all. Cancer Cell. 2005;7:405-7.

Siveke JT, Lubeseder-Martellato C, Lee M, Mazur PK, Nakhai H, Radtke
F, Schmid RM. Notch signaling is required for exocrine regeneration after
acute pancreatitis. Gastroenterology. 2008;134:544-55.

Prerequisite: Applicants must have a Ph.D. and/or M.D. postdoctoral training. A strong background in mouse genetics working techniques, molecular biology and molecular imaging will be of advantage. The ideal applicant is a very motivated and goal-oriented scientist.

Payment is according to tariff (TV-L).

We give priority to applicants with a disability and essentially equal qualifications.

Starting date: The position is available as from August 2009 but later starting dates are possible.

Duration: Initially for 4 years with an option for extension.

Apply to: Please send your application (including CV, list of publications, and 2-3 references)

preferentially by Email to:
Dr. Jens Siveke
(jens.siveke@lrz.tum.de),
II. Medizinische Klinik (Gastroenterologie),
Technische Universität München,
Ismaninger Straße 22, 81675 München.

KLINIKUM RECHTS DER ISAR
DER TECHNISCHEN UNIVERSITÄT MÜNCHEN
- ANSTALT DES ÖFFENTLICHEN RECHTS -

At the University of Medicine, the following positions:
In the Medical Clinic, Specialty: Endocrinology and metabolic disorders from now on, initially temporary for one year 1 veterinary medical technician Assistant (m / w) (ratio 172/09)

The group deals with, inter alia, new approaches to therapy diabetes type 1 and 2nd

Your Responsibilities:

• The focus of your activity is on the isolation of murine and procinen Langerhans islet cells as well as on the implementation of cellular assays (ELISA, FACS). After thorough training to work
They largely function independently within your area.

• Team-oriented, careful work and interest in science Questions are provided. Knowledge in the above Techniques are desirable, we are happy but also about applications of young professionals, respectively.

• We offer an interesting and responsible work in well equipped Laboratory spaces.

The compensation is based on the TV-L of the relevant fee per group once the personal and collective circumstances. Moreover We offer all the benefits of public service.

Contact to e-mail: weyande@uni-mainz.de

With appropriate suitability are severely preferred.
Full-time positions may also busy with part-time staff that their Working according to the needs of each vote.

Applications including the usual documents are processed within two weeks specifying the code sent to :
the University of Medicine of the Johannes Gutenberg-Universität Mainz,
Human Resources Service Center,
55131 Mainz, Germany.

From the living room Mainz can your children from 3 Birthday
during working hours in the "Villa Kinderhaus Nees' care.
UNIVERSITÄTSMEDIZIN
the Johannes Gutenberg University of Mainz - public corporation

Our company‘s mission is to provide new treatment options for diseases with high unmet
medical need.

We are committed to innovation and to translating ideas from basic research
into novel drugs. We are also dedicated to fostering collaborations with excellent academic
groups and start-ups. In order to further pool expertise and to join forces with scientists,
Bayer Schering Pharma AG intends to support collaborative research projects on attractive
molecular targets in the fields of

oncology • cardiology • gynecology • in vivo imaging.

Grants are meant to be provided to support research on promising targets. So if you have
discovered a novel molecular drug target and want to develop it further in cooperation with us,
please send us your proposal via our website link (www.grants4targets.com). This website
contains additional information and the terms and conditions that apply to grant allocation.

The deadlines for applications are June 30, 2009, and September 30, 2009.

The Friedrich-Baur-Institute at the Neurological Clinic Grosshadern, Laboratory of Molecular Myology (Line Priv. Dr. med M. Walter) is looking for
ENGINEER / IN Fachrichtung BIOTECHNOLOGY (FH)
to participate in a research project drittmittelgeförderten in the field of disease-specific mechanisms of de generativen muscle diseases, in particular the aggregate --
myopathy.

You have completed your studies in biotechnology or a comparable. Training with good or very good success and ideally have expertise in the field of cell biology, molecular biology and biochemistry.

We are looking for an active , good and self Staff in with fun and interest in a diverse activities in medical research. Knowledge in molecular biological and cell biological
Techniques such as DNA isolation, PCR, cell culture and Western blot and very good English written and spoken (international Exchange) are desirable. Team skills, fast
Perception and the ability to organize themselves well to be able to, we will assume.
Payment is according to TV-L pay GROUP 9 The work relationship is initially for 1 year temporary, but we are at a interested in long-term cooperation. Severely disabled applicants
inside are equally qualified preferred. The application Women will be warmly welcomed.

Applications should be sent to:
University Hospital Munich,
Neurologische Klinik und Poliklinik,
Dr. M. Walter, Dr. med Joachim Schessl,
Friedrich-Baur-Institute,
Ziemssenstr. 1, 80336 Munich,
e-mail: maggie.walter @ med.unimuenchen.de